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Open Access Article

JCIM. 2021; 1: (1) ; 87-89 ; DOI: 10.12208/j.ddjryx.2021.0036.

Analysis of the Effect of Sodium Aescinate in the Treatment of Sudden Deafness with Diabetes
七叶皂苷钠治疗伴有糖尿病的突发性聋疗效分析

作者: 郭斌, 马新春, 张英*,

青海大学附属医院耳鼻咽喉科,青海 西宁

*通讯作者: 张英,单位:青海大学附属医院耳鼻咽喉科,青海 西宁;

发布时间: 2021-01-10 总浏览量: 177

摘要

目的:观察七叶皂苷钠治疗伴有糖尿病的突发性耳聋(低频下降型)有效性及安全性。方法:以2018年06月至2020年08月在我科治疗符合突发性聋诊断标准并伴有糖尿病的患者89例为研究对象,分为七叶皂苷钠治疗组(42例)和对照组(47例)。两组均给予突发性聋临床指南中的常规治疗,治疗组在常规治疗的基础上加用注射用七叶皂苷钠,观察指标为听力疗效、耳鸣疗效、总有效率。结果:七叶皂苷钠组听力改善有效率为92.86%,耳鸣改善有效率为92.86%,总有效率为80.95%,均高于对照组,且有显著差异(P<0.05)。结论:七叶皂苷钠治疗伴有糖尿病的突发性耳聋具有较好的临床疗效且没有糖皮质激素样副作用,安全有效。

关键词: 七叶皂苷钠;糖尿病;突发性聋

Abstract

Objective:To observe the efficacy and safety of sodium aescinate in the treatment of sudden deafness(Low frequency descending type)with diabetes.
Methods:A total of 89 patients with diabetes who met the diagnostic criteria for sudden deafness and were treated in our department from June 2018 to August 2020 were selected as study subjects,and were divided into the aescinate treatment group(42 cases)and the control group(47 cases).Both groups were given the conventional treatment in clinical guidelines for sudden deafness.In the treatment group,sodium aescinate for injection was added on the basis of the conventional treatment,and the observation indexes were the efficacy of hearing,tinnitus and total effective rate.
Results:The effective rate of hearing improvement in sodium aescinate group was 92.86%,the effective rate of tinnitus was 92.86%,and the total effective rate was 80.95%,all higher than the control group,and there were significant differences(P<0.05).
Conclusion  :Sodium aescinate is safe and effective in the treatment of sudden deafness with diabetes without glucocorticoid-like side effects.

Key words: Sodium Aescinate;Diabetes;Sudden Deafness

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引用本文

郭斌, 马新春, 张英, 七叶皂苷钠治疗伴有糖尿病的突发性聋疗效分析[J]. 当代介入医学, 2021; 1: (1) : 87-89.